Ru2(CO)4(OOCR)2(PPh3)2 sawhorse-type complexes containing l2-g -carboxylato ligands derived from biologically active acids
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چکیده
The thermal reaction of Ru3(CO)12 with the biologically active acids acetyl salicylic acid (Aspirin), a-methyl-4-(isobutyl)phenylacet acid (Ibuprofen) and 3a,7a,12a-trihydroxy-5b-cholanic acid (cholic acid) in refluxing tetrahydrofuran, followed by addition of tripheny phosphine, gives the dinuclear complexes Ru2(CO)4(OOCR)2(PPh3)2 (1: R = C6H4-2-OCOMe, 2: R = CHMe-C6H4-4-Bu , 3: C23H39O3 The single-crystal structural analysis of 1 and 2 reveals a dinuclear Ru2(CO)4 sawhorse structure, the diruthenium backbone bein bridged by the carboxylato ligands, while the two phosphine ligands occupy the axial positions at the ruthenium atoms. However, chira carbon atoms in the carboxylic acid undergo racemisation during the thermal reaction.
منابع مشابه
Ru2(CO)4(OOCR)2L2 sawhorse-type complexes containing axial 5-(4-pyridyl)-10,15,20-triphenylporphyrin ligands
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